globe
  1. Core Texts 5 items
    1. Principles of Genetics - Eldon J. Gardner 1991

      Book Further

    2. Genes IX - Benjamin Lewin 2008

      Book Further

    3. Molecular Biology of the Cell - Bruce Alberts 2015

      Book Further

    4. Molecular Cell Biology - Harvey F. Lodish 2016

      Book Further

    5. Human Molecular Genetics - T. Strachan, Andrew P. Read, Tom Strachan 2011

      Book Further

  2. Lecture 1: How to Design a Eukaryotic Expression Vector 5 items
    1. General Information on Eukaryotic Gene Expression: 5 items
      1. Nucleic Acid Structure and Gene Expression - T. Strachan, Andrew P. Read 2011

        Chapter Essential

      2. Organisation of the Human Genome - T. Strachan, Andrew P. Read 2011

        Chapter Essential

      3. Human Gene Expression - T. Strachan, Andrew P. Read 2011

        Chapter Essential

  3. Lecture 2: Controlling Gene Expression in Mammalian Vectors 7 items
    1. Reading 7 items
      1. Control of Beta Globin Genes - Milind C. Mahajan, Subhradip Karmakar, Sherman M. Weissman 2007

        Article 

  4. Lecture 3: How to Choose a Eukaryotic Expression Vector 9 items
    1. Reading 9 items
      1. Gene Approaches to Treating Disease - T. Strachan, A. Read 2011

        Chapter Recommended

  5. Lecture 4: Electronic Cloning 0 items
    Workshop - No suggested reading
  6. Lecture 5: Down-Regulating Mammalian Genes at the RNA Level 8 items
    1. Reading 8 items
      1. Organisation of the Human Genome - T. Strachan, A. Read 2011

        Chapter 

      2. Catalytic RNA - Cassandra R Burke, Andrej Lupták

        Chapter Recommended

  7. Reading Week: 0 items
    No suggested reading
  8. Lecture 6: Lentiviral Vectors: A Leading Integrative Gene Expression System 6 items
    1. Reading 6 items
      1. Lentiviral Vectors, Two Decades Later - L. Naldini, D. Trono, I. M. Verma 2016

        Article Recommended

      2. Gene Therapy: Twenty-First Century Medicine - Inder M. Verma, Matthew D. Weitzman 2005

        Article Recommended

  9. Lecture 7: Lentiviral Vectors: Towards Clinical Success 7 items
    1. Reading 7 items
      1. Integration-Deficient Lentiviral Vectors: A Slow Coming of Age - Klaus Wanisch, Rafael J Yáñez-Muñoz 2009

        Article Recommended

      2. Clinical Use of Lentiviral Vectors - Michael C. Milone, Una O’Doherty 2018

        Article Recommended

  10. Lecture 8: Arming the Immune System 6 items
    1. Reading 6 items
      1. Clinical Development of CAR T Cells—challenges and Opportunities in Translating Innovative Treatment Concepts - Jessica Hartmann, Martina Schüßler‐Lenz, Attilio Bondanza, Christian J Buchholz 2017

        Article Recommended

  11. Lecture 9: Adeno-Associated Viral Vectors: Little Guys With a Punch 5 items
    1. AAV Biology, Infectivity and Therapeutic Use From Bench to Clinic - Melisa A. Vance, Angela Mitchell, Richard J. Samulski

      Chapter Recommended

    2. Engineering Adeno-Associated Viruses for Clinical Gene Therapy - Melissa A. Kotterman, David V. Schaffer 2014

      Article Recommended

  12. Christmas Break 0 items
  13. Lecture 1: Using an Amoeba as a Research Model 7 items
    1. Reading 7 items
      1. Dictyostelium as a Biomedical Model - Katrina Boeckeler, Robin SB Williams

        Chapter Recommended

      2. Chemoattractant Signaling In - Carol L. Manahan, Pablo A. Iglesias, Yu Long, Peter N. Devreotes 2004

        Article Essential

      3. Directional Sensing During Chemotaxis - Christopher Janetopoulos, Richard A. Firtel 2008

        Article Essential

  14. Lecture 2: Neuropsychiatric Research in a Simple Model 8 items
    1. Reading 8 items
      1. Pharmacogenetics: Defining the Genetic Basis of Drug Action and Inositol Trisphosphateanalysis - Kathryn E. Adley, Melanie Keim, Robin S. B. Williams 2006

        Chapter Essential

      2. A Common Mechanism of Action for Three Mood-Stabilizing Drugs - Robin S. B. Williams, Lili Cheng, Anne W. Mudge, Adrian J. Harwood 2002

        Article Essential

      3. GSK-3 Activity in Neocortical Cells Is Inhibited by Lithium but Not Carbamazepine or Valproic Acid - W Jonathan Ryves, Emma C Dalton, Adrian J Harwood, Robin SB Williams 2005

        Article Essential

      4. Mood Stabilizers and the Cell Biology of Neuronal Growth Cones - Britta J. Eickholt, Robin S.B. Williams, Adrian J. Harwood 2004

        Article Recommended

  15. Lecture 3: Make it Green - Using GFP in Research 9 items
    1. Reading 9 items
      1. A New Set of Small, Extrachromosomal Expression Vectors for Dictyostelium Discoideum - Douwe M. Veltman, Gunkut Akar, Leonard Bosgraaf, Peter J.M. Van Haastert 2009

        Article Essential

      2. Dictyostelium: Cell Sorting and Patterning - Cornelis J. Weijer, Jeffrey G. Williams 2009 (electronic book)

        Chapter Essential Encyclopedia of Life Sciences, see www.els.net

      3. A Brilliant Monomeric Red Fluorescent Protein to Visualize Cytoskeleton Dynamics in Dictyostelium - Markus Fischer, Ilka Haase, Evelyn Simmeth, Günther Gerisch 2004

        Article Essential

      4. Visualizing Cytoskeleton Dynamics in Mammalian Cells Using a Humanized Variant of Monomeric Red Fluorescent Protein - Markus Fischer, Ilka Haase, Sebastian Wiesner, Annette Müller-Taubenberger 2006

        Article Essential

      5. The Green Fluorescent Protein - Roger Y. Tsien 1998

        Article Recommended

      6. Zizimin and Dock Guanine Nucleotide Exchange Factors in Cell Function and Disease - Nicholl K. Pakes, Douwe M. Veltman, Robin S.B. Williams 2013

        Article Recommended

  16. Lecture 4: Epilepsy and Health Research in Dictyostelium 4 items
    1. Reading 4 items
      1. One Stop Shop for Everything Dictyostelium: dictyBase and the Dicty Stock Center in 2012 - Petra Fey, Robert J. Dodson, Siddhartha Basu, Rex L. Chisholm 2013

        Chapter Essential

  17. Lecture 5: Social Behaviour in an Amoeba 15 items
    1. Reading 15 items
      1. Non-Catalytic Roles of Presenilin Throughout Evolution - Grant P. Otto, Devdutt Sharma, Robin S.B. Williams 2016

        Article Recommended

      2. Pleiotropy as a Mechanism to Stabilize Cooperation - Kevin R. Foster, Gad Shaulsky 2004

        Article Essential

      3. The Cold War of the Social Amoebae - Gad Shaulsky, Richard H. Kessin 2007

        Article 

      4. Dictyostelium: Cell Sorting and Patterning - Cornelis J. Weijer, Jeffrey G. Williams 2009

        Chapter Essential Encyclopedia of Life Sciences, see www.els.net

  18. Reading Week: 0 items
  19. Lecture 6: Gene Editing: Permanent Genetic Modification 6 items
    1. Modeling Human Disease in Rodents by CRISPR/Cas9 Genome Editing - Marie-Christine Birling, Yann Herault, Guillaume Pavlovic 2017

      Article Recommended

  20. Lecture 7: Applications of Gene Editing 4 items
    1. Generation of Genetically-Engineered Animals Using Engineered Endonucleases - Jong Geol Lee, Young Hoon Sung, In-Jeoung Baek 2018

      Article Recommended

  21. Lecture 8: Potential of Gene Editing as a Gene Therapy 9 items
    1. Genome-Edited T Cell Therapies - Juliette M. K. M. Delhove, Waseem Qasim 2017

      Article Recommended

    2. The Therapeutic Landscape of HIV-1 via Genome Editing - Alexander Kwarteng, Samuel Terkper Ahuno, Godwin Kwakye-Nuako 2017

      Article Recommended

  22. Lecture 9: Recent Cutting Edge Advances in Gene Editing 4 items
    1. Cas9, Cpf1 and C2c1/2/3―What's Next? - Shota Nakade, Takashi Yamamoto, Tetsushi Sakuma 2017

      Article Recommended

  23. Lecture 10: Ethical Consideration of Gene Editing 4 items
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