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  1. Study and Communication Skills for the Biosciences - Stuart Johnson, Jon Scott 2014

    Book Recommended A good advice on study skills may be found in this book.

  2. Key Essential Bibliography: 3 items
    Use one of these two essential books. Other Biochemistry textbooks might be suitable, ask if in doubt. On-line materials are available, e.g. see publishers' websites (Wiley). For topics not covered by the above, sources will be recommended during the lectures.
    1. Biochemistry - Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, Lubert Stryer 2015

      Book Essential 7th edition, or later, acceptable

    2. Biochemistry - Donald Voet, Judith G. Voet 2011

      Book Essential 3rd edition, or later, acceptable

    3. Principles of Biochemistry - Donald Voet, Judith G. Voet, Charlotte W. Pratt 2013

      Book Recommended Newer International Editions available

  3. Term 1. Week 3. 7 items
    1. Textbook Reading: 2 items
      1. Biochemistry - Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, Lubert Stryer 2015

        Book Recommended Chapter 3 - Exploring Proteins and Proteomes, all sections

      2. Biochemistry - Donald Voet, Judith G. Voet 2011

        Book Recommended Chapter 6

    2. Additional Reading: 5 items
      1. Extraction/Fractionation Techniques for Proteins and Peptides and Protein Digestion - Daniel Martínez-Maqueda, Blanca Hernández-Ledesma, Lourdes Amigo, Beatriz Miralles 2013

        Chapter Further

  4. Term 1. Week 4: 6 items
    Principles of Protein Structure:
    1. Textbook Reading: 2 items
      1. Biochemistry - Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, Lubert Stryer 2015

        Book Recommended Chapters 2 and 6 (all sections)

      2. Biochemistry - Donald Voet, Judith G. Voet 2011

        Book Recommended Chapters 4, 7, and 8

    2. Additional Reading: 4 items
      1. Amino Acid Properties and Consequences of Substitutions - Matthew J. Betts, Robert B. Russell 2003

        Chapter Further

      2. Conformations of Amino Acids in Proteins - Sven Hovmöller, Tuping Zhou, Tomas Ohlson 2002

        Article Further

      3. Subunit Arrangement and Function in NMDA Receptors - Hiroyasu Furukawa, Satinder K Singh, Romina Mancusso, Eric Gouaux 2005

        Article Further

  5. Term 1. Week 5: 14 items
    Protein folding. Analysis and prediction of protein structure and function.
    1. Textbook Reading: 2 items
      Relevant material may be found in many textbooks , e.g.:
      1. Biochemistry - Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, Lubert Stryer 2015

        Book Recommended Chapters 2 and 30

      2. Biochemistry - Donald Voet, Judith G. Voet 2011

        Book Recommended Chapter 9

    2. Additional Reading: 12 items
      1. Chapter 4: Human Prion Diseases - Amos D. Korczyn

        Document Further Available on Moodle

      2. Origins of Structural Diversity Within Sequentially Identical Hexapeptides - B. I. Cohen, S. R. Presnell, F. E. Cohen 1993

        Article Further

      3. Protein Folding in the Cell: Challenges and Progress - Anne Gershenson, Lila M. Gierasch 2011

        Article Further

      4. Molecular Chaperones in Protein Folding and Proteostasis - F. Ulrich Hartl, Andreas Bracher, Manajit Hayer-Hartl 2011

        Article Further

      5. Protein Folding on the Ribosome - Lisa D Cabrita, Christopher M Dobson, John Christodoulou 2010

        Article Further

      6. Cotranslational Protein Folding Inside the Ribosome Exit Tunnel - Ola B. Nilsson, Rickard Hedman, Jacopo Marino, Stephan Wickles 2015

        Article Further

      7. Conformations of Amino Acids in Proteins - Sven Hovmöller, Tuping Zhou, Tomas Ohlson 2002

        Article Further

  6. Term 1. Week 6: 15 items
    Analysis and prediction of protein structure and function (cont.).
    1. BLAST: Basic Local Alignment Search Tool

      Webpage Essential read Help files before you start using BLAST tool

    2. Alternative Sites: 3 items
      1. BLAST: Basic Local Alignment Search Tool

        Webpage Further If the above link does not work, or just Google "NCBI BLAST"

    3. Publications: 2 items
      1. Web of Science Service for UK Education - Home Page

        Article Essential Must be accessed from the college network or using VPN connection

    4. Protein Database Search: 2 items
    5. Protein Structure Database Search: 2 items
    6. Other Useful Sites: 5 items
      1. NCBI Handbook (Glossary)

        http://www.ncbi.nlm.nih.gov/books/NBK21106/

         

        Swiss-PdbViewer • analyse protein 3D structures 

      2. Integrated collection of relevant tools and links:

      3. Far more links- absolutely pages of the stuff can be found on Moodle.

  7. Week 7: Reading Week 0 items
  8. Term 1. Week 8: 6 items
    Protein Interactions. An Introduction to Protein Engineering.
    1. Additional Reading: 6 items
  9. Term 1. Week 9: 9 items
    Protein Structure and Function (Coursework)
    1. Display Systems: 7 items
      1. The Use of mRNA Display to Select High-Affinity Protein-Binding Peptides - David S. Wilson, Anthony D. Keefe, Jack W. Szostak 2001

        Article Further

      2. Phage Display - a Powerful Technique for Immunotherapy - Justyna Bazan, Ireneusz Całkosiński, Andrzej Gamian 2012

        Article Further

      3. Ribosome Display: A Perspective - Andreas Plückthun

        Chapter Further

    2. Additional Reading: 2 items
      1. Design and Evolution of Enzymes for Non-Natural Chemistry - Stephan C. Hammer, Anders M. Knight, Frances H. Arnold 2017

        Article Further

      2. Engineering Novel Binding Proteins From Nonimmunoglobulin Domains - H Kaspar Binz, Patrick Amstutz, Andreas Plückthun 2005

        Article Further

  10. Term 1. Week 10: 4 items
    Protein Structure and Function
    1. Textbook Reading: 2 items
      1. Biochemistry - Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, Lubert Stryer 2015

        Book Recommended Chapter 30 (pp. 946-948, fig. 30.34), Chapter 10 (pp. 312-324), Chapter 11 (pp. 339-355), Chapter 34 (pp. 1019-1031)

      2. Biochemistry - Donald Voet, Judith G. Voet 2011

        Book Recommended Chapter 32 (pp. 1403-1408), Chapter 11 (pp. 379-384), Chapter 12 (pp. 414-415)

    2. Reference Materials: 2 items
      1. Introduction to glycobiology - Maureen E. Taylor, Kurt Drickamer 2011

        Book Further Esp. chapters 2 and 3

      2. Essentials of Glycobiology - Ajit Varki, Richard D. Cummings, Jeffrey D. Esko 2015-2017

        Book Further

  11. Term 1. Week 11: 5 items
    Protein Structure and Function
    1. Further Sources: 5 items
      1. Mass Spectrometry Approaches to Glycomic and Glycoproteomic Analyses - L. Renee Ruhaak, Gege Xu, Qiongyu Li, Elisha Goonatilleke 2018

        Article Further

      2. ProZyme - Advancing Glycosciences-index

        Website Further Materials and methods for analysis

      3. GlycomeAtlas V5

        Webpage Further For data on human, mouse and zebrafish

  12. Term 1. Week 12: 4 items
    Protein Structure and Function
    1. Textbook Reading: 4 items
      1. Biochemistry - Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, Lubert Stryer 2015

        Book Recommended Chapters 8 and 9

      2. Biochemistry - Donald Voet, Judith G. Voet 2011

        Book Recommended Chapters 14 and 15

      3. Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins - Nicholas C. Price, Lewis Stevens 1999

        Book Recommended Especially chapters 4 and 5

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