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Cover of Essentials of Glycobiology

Essentials of Glycobiology, 3rd edition

Editors: Ajit Varki, Executive Editor, Richard D Cummings, Jeffrey D Esko, Pamela Stanley, Gerald W Hart, Markus Aebi, Alan G Darvill, Taroh Kinoshita, Nicolle H Packer, James H Prestegard, Ronald L Schnaar, and Peter H Seeberger.

Editor Information
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2015-.
Hardcopy Version at Cold Spring Harbor Laboratory PressLogo of Cold Spring Harbor Laboratory Press

Defined in the broadest sense, Glycobiology is the study of the structure, biosynthesis, biology, and evolution of saccharides (sugar chains or glycans) that are widely distributed in nature in all living life forms. Glycobiology is now one of the more rapidly growing fields in the natural sciences, with broad relevance to many areas of basic research, biomedicine, and biotechnology. The field includes the chemistry of carbohydrates, the enzymology of glycan formation and degradation, the recognition of glycans by specific proteins, roles of glycans in complex biological systems, and their analysis or manipulation by various techniques. The third edition of this primary textbook in the field continues in the prior tradition, seeking to provide basic overview of Glycobiology, directed towards the advanced undergraduate or the beginning graduate-level student of molecular and cellular biology and biomedicine. While efforts have been made to avoid a major increase in overall length of the text, substantial changes and improvements include the following: broader focus on all lineages of life forms in nature; wider range of topics, ranging from biology and medicine to chemistry and materials science; expanded international editorial board representing a wider range of expertise; wider range of contributing authors with expertise in specific areas; greatly expanded monosaccharide symbol nomenclature for the representation of glycans; and greater attention to informatics, and relevance to exploration of the glycome.

Contents

Printed in the United States of America

Publisher and Acquisition Editor John Inglis
Director of Editorial Services Jan Argentine
Project Manager Inez Sialiano
Permissions Coordinator Carol Brown
Production Editor Kathleen Bubbeo
Production Manager Denise Weiss
Cover Designer Michael Albano
Illustrator and Illustrations Coordinator Richard D. Cummings

Front cover artwork: Stereo view of a crystal structure (1TB6) of the complex between antithrombin (purple), thrombin (blue), and a 16-mer heparin mimetic (SR123781A). The proteins are shown in cartoon with a semitransparent surface, and the oligosaccharide is represented as ball-and-stick, with carbon in green, oxygen in red, and sulfur in yellow. The oligosaccharide is composed of an antithrombin-specific pentasaccharide based on idraparanux, an uncharged seven-saccharide unit linker, and a highly sulfated four residue thrombin-binding unit. Picture courtesy of Jim Huntington, Professor of Molecular Haemostasis, University of Cambridge.

Library of Congress Cataloging-in-Publication Data

Names: Varki, Ajit, editor.

Title: Essentials of glycobiology/edited by Ajit Varki [and eleven others].

Description: Third edition. | Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, [2017]

Identifiers: LCCN 2016045934 | ISBN 9781621821328 (hardcover)

Subjects: LCSH: Glycoproteins. | Glycosylation. | Glycomics. | Molecular biology.

Classification: LCC QP552.G59 E87 2017 | DDC 572/.68--dc23

LC record available at https://lccn.loc.gov/2016045934

10 9 8 7 6 5 4 3 2 1

All World Wide Web addresses are accurate to the best of our knowledge at the time of printing.

Authorization to photocopy items for internal or personal use, or the internal or personal use of specific clients, is granted by Cold Spring Harbor Laboratory Press, provided that the appropriate fee is paid directly to the Copyright Clearance Center (CCC). Write or call CCC at 222 Rosewood Drive, Danvers, MA 01923 (978-750-8400) for information about fees and regulations. Prior to photocopying items for educational classroom use, contact CCC at the above address. Additional information on CCC can be obtained at CCC Online at www.copyright.com.

For a complete catalog of all Cold Spring Harbor Laboratory Press publications, visit our website at http://www.cshlpress.org.

Full text of this work and associated links are available at http://www.ncbi.nlm.nih.gov/books/NBK310274

Copyright 2015-2017 by The Consortium of Glycobiology Editors, La Jolla, California. All rights reserved.

PDF files are not available for download.

Bookshelf ID: NBK310274PMID: 27010055

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